Cajun Spiced Salmon Salsa

Featured in: Sheet Pan Recipes

This dish features tender salmon fillets rubbed with spicy Cajun seasoning and baked to flaky perfection. The topping is a fresh and tangy salsa made with pomegranate seeds, cucumber, red onion, cilantro, jalapeño, and lime zest and juice. Olive oil and a hint of salt balance the flavors, creating a vibrant accompaniment. Served with lime wedges, it’s a colorful and healthy main best enjoyed immediately. Preparation is quick, making it ideal for weeknight meals.

Updated on Sun, 16 Nov 2025 09:43:00 GMT
Cajun Spiced Salmon glistening, topped with vibrant pomegranate salsa ready to enjoy. Save It
Cajun Spiced Salmon glistening, topped with vibrant pomegranate salsa ready to enjoy. | sunnyspoonful.com

A vibrant and flavorful dish featuring spicy Cajun-rubbed salmon fillets paired with fresh, tangy pomegranate salsa. Perfect for a healthy and impressive weeknight dinner.

The first time I made this Cajun spiced salmon, my family devoured every bite and requested it again the very next week. The combination of spicy salmon and refreshing salsa instantly won everyone over.

Ingredients

  • Salmon: 4 salmon fillets (about 150 g each), skin-on or skinless
  • Olive oil: 1 tbsp, divided use
  • Cajun seasoning: 1 tbsp
  • Salt: 1/2 tsp, plus 1/4 tsp for salsa
  • Black pepper: 1/4 tsp
  • Pomegranate seeds: 1 cup (arils)
  • Cucumber: 1/2 cup diced
  • Red onion: 1/4 cup finely chopped
  • Fresh cilantro: 1/4 cup chopped
  • Jalapeño: 1 seeded and finely diced
  • Lime: Zest and juice of 1
  • Lime wedges: For serving

Instructions

Prep:
Preheat oven to 200°C (400°F). Line a baking tray with parchment paper.
Season:
Pat salmon fillets dry with paper towels. Rub each piece with olive oil, Cajun seasoning, salt, and black pepper. Arrange fillets on the prepared tray, skin-side down if using skin-on salmon.
Bake:
Bake salmon for 10–12 minutes, until just cooked through and flaky.
Salsa:
While the salmon bakes, gently combine pomegranate seeds, cucumber, red onion, cilantro, jalapeño, lime zest and juice, olive oil, and salt in a bowl.
Serve:
Plate salmon and top each piece with the pomegranate salsa. Serve with lime wedges.
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Sharing this colorful salmon at the table always sparks lively conversation. Even picky eaters in our home love the sweet-tart salsa that balances the bold spices.

Serving Suggestions

This dish shines with a side of quinoa, rice, or roasted vegetables for a complete meal.

Allergen Information

Contains fish (salmon). Cajun seasoning may include mustard or other allergens—always check labels. Naturally gluten-free and dairy-free.

Nutrition Info

Each serving contains 340 calories, 16 g fat, 15 g carbohydrates, and 33 g protein.

Perfectly cooked Cajun Spiced Salmon with a colorful salsa, lime wedges offer a zesty finish. Save It
Perfectly cooked Cajun Spiced Salmon with a colorful salsa, lime wedges offer a zesty finish. | sunnyspoonful.com

This Cajun spiced salmon is sure to become a weeknight favorite, bringing vibrant color and delicious flavor to your table.

Recipe FAQs

What type of salmon works best?

Both skin-on and skinless salmon fillets work well. Skin-on adds extra flavor and helps keep the salmon moist during baking.

Can I adjust the heat level?

Yes, for more spice, add cayenne pepper to the Cajun seasoning or include extra jalapeño in the salsa.

How fresh should the pomegranate seeds be?

Use fresh pomegranate seeds for the best burst of sweetness and texture in the salsa. Frozen seeds can be used but may be less crisp.

What sides pair well with this dish?

Quinoa, rice, or roasted vegetables complement the savory and tangy flavors beautifully.

Is this suitable for gluten-free and dairy-free diets?

Yes, the ingredients used are naturally gluten-free and dairy-free, but always verify spice blends to avoid hidden allergens.

Cajun Spiced Salmon Salsa

Flavorful Cajun-seasoned salmon fillets topped with fresh, zesty pomegranate salsa and lime wedges.

Prep Time
15 mins
Cook Time
12 mins
Total Duration
27 mins
Authored by Lana Bright

Recipe Type Sheet Pan Recipes

Skill Level Easy

Cuisine Style American, Cajun

Recipe Yield 4 Serving Size

Diet Preferences Dairy-Free, Free From Gluten

What You'll Need

Salmon

01 4 salmon fillets (5.3 oz each), skin-on or skinless
02 1 tablespoon olive oil
03 1 tablespoon Cajun seasoning
04 1/2 teaspoon salt
05 1/4 teaspoon black pepper

Pomegranate Salsa

01 1 cup pomegranate seeds
02 1/2 cup diced cucumber
03 1/4 cup finely chopped red onion
04 1/4 cup chopped fresh cilantro
05 1 jalapeño, seeded and finely diced
06 Zest and juice of 1 lime
07 1 tablespoon olive oil
08 1/4 teaspoon salt

To Serve

01 Lime wedges

Directions

Step 01

Preheat Oven: Set the oven to 400°F and line a baking tray with parchment paper.

Step 02

Prepare Salmon: Pat salmon fillets dry, rub with olive oil, Cajun seasoning, salt, and black pepper. Arrange fillets skin-side down on the tray if skin is on.

Step 03

Bake Salmon: Bake the salmon for 10 to 12 minutes until opaque and flaky.

Step 04

Make Pomegranate Salsa: In a medium bowl, gently combine pomegranate seeds, cucumber, red onion, cilantro, jalapeño, lime zest and juice, olive oil, and salt.

Step 05

Plate and Serve: Remove salmon from oven, plate fillets, and spoon salsa over each. Serve immediately with lime wedges.

Tools You'll Need

  • Baking tray
  • Parchment paper
  • Mixing bowls
  • Sharp knife
  • Cutting board

Allergy Information

Review each ingredient to identify potential allergens, and consult a healthcare professional if you're unsure.
  • Contains fish (salmon).
  • Cajun seasoning may contain mustard or other allergens; check labels if sensitive.

Nutrition Details (Per Serving)

This nutritional data is for reference only and isn't a substitute for medical advice.
  • Caloric Value: 340
  • Fats: 16 grams
  • Carbohydrates: 15 grams
  • Proteins: 33 grams