Baked Pesto Chicken Mac & Cheese

Featured in: Hearty Dinners

This comforting casserole combines tender pesto-seasoned chicken with creamy macaroni in a rich three-cheese sauce. The dish features a golden, crispy breadcrumb topping that adds perfect texture to each bite. With mozzarella, Parmesan, and sharp cheddar melted throughout, every serving delivers satisfying comfort food that's ideal for weeknight dinners or family gatherings.

Updated on Wed, 04 Feb 2026 22:18:32 GMT
Golden, bubbly Baked Pesto Chicken Mac & Cheese casserole served hot from the oven. Save It
Golden, bubbly Baked Pesto Chicken Mac & Cheese casserole served hot from the oven. | sunnyspoonful.com

Baked Pesto Chicken Mac & Cheese is a comforting casserole that brings together juicy pesto-seasoned chicken, creamy macaroni, and a perfectly golden cheese crust. This dish is ideal for weeknight dinners or family gatherings, offering a satisfying blend of savory Italian herbs and classic American comfort.

Golden, bubbly Baked Pesto Chicken Mac & Cheese casserole served hot from the oven. Save It
Golden, bubbly Baked Pesto Chicken Mac & Cheese casserole served hot from the oven. | sunnyspoonful.com

This recipe elevates a traditional macaroni and cheese by incorporating a savory pesto chicken element. The combination of three different cheeses provides a multi-dimensional sauce that perfectly complements the herb-infused chicken pieces, making it a crowd-pleasing favorite for all ages.

Ingredients

  • 400 g (14 oz) elbow macaroni
  • 500 g (1.1 lb) boneless, skinless chicken breast, cut into bite-sized pieces
  • 2 tbsp olive oil
  • 1/2 tsp salt
  • 1/4 tsp black pepper
  • 1/2 tsp dried Italian herbs
  • 100 g (1/2 cup) basil pesto (store-bought or homemade)
  • 3 tbsp unsalted butter
  • 3 tbsp all-purpose flour
  • 700 ml (3 cups) whole milk
  • 150 g (1 1/2 cups) shredded mozzarella cheese
  • 100 g (1 cup) shredded Parmesan cheese
  • 100 g (1 cup) shredded sharp cheddar cheese
  • 1/2 tsp garlic powder
  • Salt and pepper, to taste
  • 40 g (1/2 cup) panko breadcrumbs
  • 30 g (1/4 cup) grated Parmesan cheese
  • 1 tbsp olive oil
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Instructions

Step 1
Preheat oven to 200°C (400°F). Grease a large baking dish (about 23x33 cm/9x13 in).
Step 2
Bring a large pot of salted water to a boil. Cook macaroni until al dente, drain, and set aside.
Step 3
While pasta cooks, heat 2 tbsp olive oil in a skillet over medium heat. Add chicken, season with salt, pepper, and Italian herbs. Cook until golden and cooked through, about 6–8 minutes. Remove from heat and toss with basil pesto.
Step 4
In a large saucepan, melt butter over medium heat. Whisk in flour and cook for 1 minute. Gradually whisk in milk, stirring constantly until thickened (about 4–5 minutes).
Step 5
Remove from heat and stir in mozzarella, Parmesan, cheddar, and garlic powder. Season with salt and pepper.
Step 6
Combine cooked macaroni, cheese sauce, and pesto chicken in a large bowl. Mix gently to coat.
Step 7
Spoon mixture into prepared baking dish.
Step 8
In a small bowl, combine panko, Parmesan, and olive oil. Sprinkle evenly over casserole.
Step 9
Bake for 20–25 minutes until bubbling and golden brown on top.
Step 10
Let rest 5 minutes before serving.

Zusatztipps für die Zubereitung

For a quicker preparation on busy nights, you can substitute the chicken breasts with a pre-cooked rotisserie chicken. Simply shred the meat and toss it with the pesto before combining it with the pasta and sauce.

Varianten und Anpassungen

Add a pop of color and extra nutrients by folding in sautéed spinach or chopped sun-dried tomatoes. You can also vary the cheese profile by using smoked gouda or fontina for a different flavor experience.

Serviervorschläge

This rich and creamy pasta dish pairs beautifully with a crisp green salad to provide a refreshing contrast. For a complete dining experience, serve it with a glass of chilled Sauvignon Blanc.

Creamy Baked Pesto Chicken Mac & Cheese with a crispy panko Parmesan topping. Save It
Creamy Baked Pesto Chicken Mac & Cheese with a crispy panko Parmesan topping. | sunnyspoonful.com

Whether you are serving a hungry family or hosting a casual dinner with friends, this Baked Pesto Chicken Mac & Cheese is a guaranteed hit that combines the best of two culinary worlds.

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Recipe FAQs

Can I make this ahead of time?

Yes, assemble the entire casserole up to 24 hours ahead, cover tightly, and refrigerate. Add 5-10 minutes to baking time if baking cold from the refrigerator.

What pasta shape works best?

Elbow macaroni is traditional, but cavatappi, penne, or shells also work well. Choose shapes with plenty of surface area to hold the creamy cheese sauce.

Can I use rotisserie chicken?

Absolutely. Shred a store-bought rotisserie chicken and toss with the pesto. This shortcut reduces prep time to about 10 minutes.

How do I store leftovers?

Cool completely, then store in an airtight container in the refrigerator for up to 4 days. Reheat individual portions in the microwave or cover the whole dish with foil and warm at 180°C (350°F) until heated through.

Can I freeze this casserole?

Yes, freeze before baking. Wrap tightly in plastic wrap and foil for up to 3 months. Thaw overnight in the refrigerator, then bake as directed, adding 10-15 minutes to the baking time.

What cheese substitutes work well?

Try smoked gouda for depth, fontina for excellent melt, or gruyère for nutty flavor. Keep the total cheese quantity the same for proper sauce consistency.

Baked Pesto Chicken Mac & Cheese

Creamy macaroni with pesto chicken and golden cheese crust

Prep Time
20 mins
Cook Time
35 mins
Total Duration
55 mins
Authored by Lana Bright

Recipe Type Hearty Dinners

Skill Level Medium

Cuisine Style American-Italian

Recipe Yield 6 Serving Size

Diet Preferences None specified

What You'll Need

Pasta

01 14 oz elbow macaroni

Chicken

01 1.1 lb boneless, skinless chicken breast, cut into bite-sized pieces
02 2 tablespoons olive oil
03 1/2 teaspoon salt
04 1/4 teaspoon black pepper
05 1/2 teaspoon dried Italian herbs

Pesto

01 1/2 cup basil pesto

Sauce

01 3 tablespoons unsalted butter
02 3 tablespoons all-purpose flour
03 3 cups whole milk
04 1.5 cups shredded mozzarella cheese
05 1 cup shredded Parmesan cheese
06 1 cup shredded sharp cheddar cheese
07 1/2 teaspoon garlic powder
08 Salt and pepper to taste

Topping

01 1/2 cup panko breadcrumbs
02 1/4 cup grated Parmesan cheese
03 1 tablespoon olive oil

Directions

Step 01

Prepare baking dish: Preheat oven to 400°F. Grease a 9x13 inch baking dish with cooking spray or butter.

Step 02

Cook macaroni: Bring a large pot of salted water to a boil. Add elbow macaroni and cook until al dente according to package directions. Drain and set aside.

Step 03

Cook chicken: While pasta cooks, heat 2 tablespoons olive oil in a skillet over medium heat. Add chicken pieces and season with salt, pepper, and Italian herbs. Cook 6-8 minutes until golden and cooked through. Remove from heat and toss with basil pesto until evenly coated.

Step 04

Create cheese sauce: In a large saucepan, melt butter over medium heat. Whisk in flour and cook for 1 minute. Gradually whisk in milk, stirring constantly until the mixture thickens, about 4-5 minutes.

Step 05

Incorporate cheese: Remove from heat and stir in mozzarella, Parmesan, cheddar cheese, and garlic powder. Season with salt and pepper to taste.

Step 06

Combine components: In a large mixing bowl, combine cooked macaroni, cheese sauce, and pesto chicken. Gently mix until evenly coated with sauce.

Step 07

Transfer to baking dish: Spoon the macaroni and chicken mixture into the prepared 9x13 inch baking dish, spreading evenly.

Step 08

Prepare topping: In a small bowl, combine panko breadcrumbs, grated Parmesan cheese, and 1 tablespoon olive oil. Mix until breadcrumbs are moistened.

Step 09

Add topping and bake: Sprinkle the panko mixture evenly over the casserole. Bake for 20-25 minutes until the mixture is bubbling around the edges and the topping is golden brown.

Step 10

Rest and serve: Remove from oven and let rest for 5 minutes before serving. This allows the casserole to set slightly for cleaner portions.

Tools You'll Need

  • Large pot for pasta cooking
  • Skillet for chicken preparation
  • Large saucepan for cheese sauce
  • Mixing bowls
  • Whisk for sauce preparation
  • 9x13 inch baking dish
  • Measuring cups and spoons

Allergy Information

Review each ingredient to identify potential allergens, and consult a healthcare professional if you're unsure.
  • Contains gluten from pasta, all-purpose flour, and panko breadcrumbs
  • Contains dairy including milk, butter, and multiple cheeses
  • Check store-bought pesto for potential tree nuts, particularly pine nuts
  • Verify all packaged ingredients for cross-contamination warnings if serving individuals with severe allergies

Nutrition Details (Per Serving)

This nutritional data is for reference only and isn't a substitute for medical advice.
  • Caloric Value: 620
  • Fats: 30 grams
  • Carbohydrates: 52 grams
  • Proteins: 36 grams